Antiparkinson drug - Mucuna pruriens shows antioxidant and metal chelating activity

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Mucuna pruriens in Parkinson disease

OBJECTIVE To investigate whether Mucuna pruriens (MP), a levodopa-containing leguminous plant growing in all tropical areas worldwide, may be used as alternative source of levodopa for indigent individuals with Parkinson disease (PD) who cannot afford long-term therapy with marketed levodopa preparations. METHODS We investigated efficacy and safety of single-dose intake of MP powder from roas...

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Antitumor Activity and In Vivo Antioxidant Status of Mucuna Pruriens (Fabaceae) Seeds against Ehrlich Ascites Carcinoma in Swiss Albino Mice

The aim of the present study is to evaluate the antitumor effect and antioxidant role of Mucuna pruriens (Family: Fabaceae) against EAC bearing Swiss albino mice. The effect of methanol extract of Mucuna pruriens (MEMP) on tumor growth and hosts survival time was studied by the following parameters: tu-mor volume, packed cell volume, viable and non-viable cell count and life span of the host. M...

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Levodopa in Mucuna pruriens and its degradation

Mucuna pruriens is the best known natural source of L-dopa, the gold standard for treatment of Parkinsonism. M. pruriens varieties are protein rich supplements, and are used as food and fodder worldwide. Here, we report L-dopa contents in seeds of fifty six accessions of four M. pruriens varieties, M. pruriens var. pruriens, M. pruriens var. hirsuta, M. pruriens var. utilis and M. pruriens var....

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Toxicity Assessment of Mucuna Pruriens Linn. Seeds

Plants have been used as medicine for the treatment of diseases for thousands of years. These herbal remedies, although natural, can cause some serious damaging effects on the vital organs of the body due to inadequacy in standardization and safety regulations. Mucuna pruriens Linn. belongs to family Fabaceae and is used traditionally in various ailments. The present study reports the acute sys...

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Phytochemical Analysis and Antioxidant Property of Leaf Extracts of Vitex doniana and Mucuna pruriens

Oxidative stress and impaired antioxidant system have been implicated in the pathophysiology of diverse disease states. The phytochemical screening and antioxidant property of fresh leaves of Vitex doniana and Mucuna pruriens, used in the management and treatment of various diseases, were studied. The extracts (ethanol and distilled water) were screened for the presence of phytochemicals, and t...

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ژورنال

عنوان ژورنال: Phytotherapy Research

سال: 2007

ISSN: 0951-418X

DOI: 10.1002/ptr.2109